| Rank | Player | Team | L |
|---|---|---|---|
| 1 |  Trevor WIlliams |  | 8 |
| 2 |  Dinelson Lamet |  | 6 |
| 3 |  Joe Gatto |  | 5 |
| 4 |  Blake Snell | | 5 |
| 5 |  Mike Foltynewicz | | 5 |
| 6 |  Aaron Nola |  | 5 |
| 7 |  Justus Sheffield |  | 5 |
| 8 |  Aaron Civale |  | 5 |
| 9 |  Patrick Corbin |  | 5 |
| 10 |  Jordan Montgomery |  | 5 |
| 11 |  John Means | | 5 |
| 12 |  Jorge Lopez | | 5 |
| 13 |  Jameson Taillon | | 5 |
| 14 |  Mike Clevinger | | 5 |
| 15 |  Hyun Jin Ryu |  | 5 |
| 16 |  Yu Darvish | | 4 |
| 17 |  Rich Hill | | 4 |
| 18 |  Shohei Ohtani | | 4 |
| 19 |  Vince Velasquez | | 4 |
| 20 |  Lucas Giolito |  | 4 |
