| Rank | Player | Team | SO |
|---|---|---|---|
| 1 |  Tyler O’Neill |  | 32 |
| 2 |  Giancarlo Stanton |  | 31 |
| 3 |  Paul Goldschmidt | | 28 |
| 4 |  Aaron Judge | | 27 |
| 5 |  Nolan Arenado | | 26 |
| 6 |  Paul DeJong |  | 25 |
| 7 |  Harrison Bader | | 24 |
| 8 |  Lourdes Gurriel Jr. |  | 23 |
| 9 |  Adam Duvall |  | 23 |
| 10 |  Jose Abreu |  | 23 |
| 11 |  Matt Carpenter |  | 22 |
| 12 |  Nelson Cruz |  | 22 |
| 13 |  Tim Anderson | | 19 |
| 14 |  Tom Murphy |  | 17 |
| 15 |  Ian Happ |  | 17 |
| 16 |  Mitch Garver | | 17 |
| 17 |  Marcus Semien | | 17 |
| 18 |  Brett Gardner | | 17 |
| 19 |  Bo Bichette | | 17 |
| 20 |  Kyle Schwarber | | 17 |
